In its place, those looking to infect systems with malware appear to have turned to the Neutrino exploit kit, according to Nicholas Griffin, a senior security researcher.
Exploit kits are used in a process known as a drive-by download which directs a browser to a Website that hosts the kit. The kit is then used to infect the system, depending on the vulnerabilities present.
The process is generally unknown to the user, happening without his or her intervention.
On a blog devoted to malware issues, the author known as Kaffeine said that those who had been using Angler were now moving to another exploit kit known as Neutrino.
Demand and supply is equally at work in the world of exploit kits and Kaffeine had noted that the suppliers of Neutrino had now increased the price of their exploit kit, Griffin said.
From US$880 per week on a shared server and US$3500 per month on a dedicated server, Neutrino was now only catering to dedicated servers and had doubled the price to US$7000, Kaffeine noted.
This is akin to what happened to exploit kit prices after the infamous Blackhole kit went out of use.
"We will continue to monitor Angler to see if it re-emerges or if it is truly dead and buried," Griffin said. "In its absence we expect to see a sharp increase in hits on other active exploit kits such as RIG and Neutrino."