The South Australian Government announced that CSC would provide and support desktop PCs, laptops and tablets to its agencies.
It said that 400 jobs would be created in the state as a result of the contract being granted to the American firm.
Out of the nearly 1000 South Australian workers who will lose their jobs at Holden, when the car manufacturer ceases Australian production in October, 30 will be reskilled and provided employment opportunities by CSC.
The government said it would save $11 million a year due to the new arrangements. The contract will run for seven years and during that period CSC will spend $5 million to set up a new office in Adelaide and raise its employee numbers from 100 to more than 700 by the end of the contract.
South Australian premier Jay Weatherill described the new arrangement as a "win-win-win for taxpayers, the government and the economy".
He said: "The broader economic and employment benefits that will flow from CSC winning the contract are significant. They have committed to establish a local partner network for small to medium local enterprises across the state that will support this new contract.
"Collectively, these SMEs will employ 100 South Australians and invest over $30 million in job creation over the contract period."
CSC Australia and New Zealand managing director Seelan Nayagam said: "CSC is delighted to be partnering with the South Australian Government on its transformation to a digital workplace.
"We commend the SA Government for initiating a technology initiative of this scale which will see the rollout of CSC’s next generation offerings and solutions – all aimed at enabling a modern and efficient public service – whilst stimulating the South Australian economy and creating jobs.
"Today’s announcement is a demonstration of CSC’s commitment to making a positive impact and ensuring a brighter future for South Australians. We are confident this programme will set a benchmark and create a blueprint for other public sector agencies across Australia."
CSC has been a technology provider to Commonwealth Bank and other businesses and governments. It was embroiled in an alleged bribery scandal at the CBA in 2015 and also charged with accounting fraud and fined US$190 million by the US Securities and Exchange Commission the same year.