The centre is to be used for chip development and the site is in the village of Sawston, close to the offices of Japanese semiconductor maker ARM Holdings, the report says.
The site was bought in 2018 by Henk Koopmans, the chief executive of Huawei R&D in the UK. The South Cambridgeshire District Council will decide on the first phase on Thursday and has been told to approve Huawei's plan.
The British Government is in the midst of a review of its policy of granting Huawei permission to supply up to 35% of gear for the non-core parts of 5G networks in the UK.
Spanish group Telefonica owns O2 and it has used Huawei’s infrastructure in some of its other networks. O2 has no wide use of Huawei in the UK, but has a network-sharing agreement with Vodafone.
The companies relied on interim advice from the government of Theresa May, leaked in April 2019, that this would be the government's final stance.
The Times quoted former first secretary of state Damian Green as saying: “Announcements like this R&D centre are clearly designed to influence the debate and they shouldn’t be allowed to influence it.
“The government calls Huawei a high-risk vendor and I want to see a path towards zero involvement from Huawei in the 5G network.”
Britain's National Cyber Security Centre is conducting another inquiry into Huawei's equipment after a push from the US Government and a number of Conservative MPs.
iTWire has contacted Huawei for comment.