Activision said the hugely anticipated action game, released yesterday for PS3, Xbox 360, Wii U and PC, sold $US1 billion ($A1.06 billion) worth of copies in just its first day of release.
"Call of Duty: Ghosts has delivered yet another epic thrill ride in the campaign, and what I think is our best multiplayer game yet," said Eric Hirshberg, chief executive of Activision Publishing.
The company noted however that the US$1 billion number was for sales to retail store, which may not reflect consumer purchases, though it said that Call of Duty is undoubtedly "the largest console franchise of this generation". The title was launched at 15,000 midnight openings around the world.
Grand Theft Auto V took more than a billion US dollars in consumer sales in its first three days of release back in September.
Analysts have said mixed review scores won't hurt the game's chances.
"We think [Call of Duty] has become such an embedded franchise that it is somewhat review-proof," said Creutz to GamesIndustry.
Noting that reviews of the recently released Call of Duty: Ghosts have reached 74 out of 100 on review aggregator Metacritic, Creutz said that "we think of [Call of Duty] as being like EA's Madden NFL, which continues to sell similar unit numbers year in and year out, regardless of reviews; Madden's Metacritic has ranged as low as 78 in recent years."
Because the blockbuster shooter franchise "changes only incrementally from year to year," adds Creutz, he thinks "reviewers have become increasingly less likely to give very high review scores due to a certain degree of ennui with the franchise."
Unsurprisingly, Activision said that since its release, Call of Duty: Ghosts has moved to the number one spot as the most played game on Xbox Live.
The game is still yet to be released on Sony's PS4 and Microsoft's Xbox One, which will both be released this month.