Kaspersky's integrated security product, Kaspersky Scan Engine, will automatically scan files when they are uploaded, the company said in a statement.
"The cross-platform nature of Nextcloud, with clients on mobile and desktop operating systems, means users can unknowingly upload and share infected files that might not affect their device, or even intentionally try to spread them through a public Nextcloud instance," Nextcloud said.
"The integrated anti-virus scan will intercept and block the upload on the server side, making sure the file is not distributed to other users."
"By integrating Kaspersky’s powerful protection capabilities, enterprises can rest assured malicious content cannot easily spread through their document exchange technology."
Alexander Karpitsky, head of Kaspersky Technology Alliances, said: “The integration of Kaspersky anti-malware technology into Nextcloud’s product provides its customers with the certainty that files accessed through or downloaded from their content collaboration platform will be secure.
"It is extremely difficult for businesses to fight millions of Web threats on their own – that’s why technology partners are needed. Together we can make our online world safer."
Nextcloud said business customers could install the Nextcloud anti-virus application from the app store and contact it for support and the required Kaspersky Scan Engine component.