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Dysport approved by FDA for wrinkle treatment

Science - Health

The U.S. Food and Drug Administration (FDA) made the announcement on Saturday, May 2, 2009, that is had approved the branded name Dysport as a way to treat forehead wrinkles and frown lines.


Dysport, previously called Reloxin, is made from the type A toxin called Clostridium botulinim. It works by relaxing the muscles that are causing the wrinkles and worry lines, what are also called glabellar lines.

According to the website of the drug’s maker Ipsen Biopharm, Dysport is scientifically called abobotulinumtoxinA.

This new wrinkle drug is made from the same active ingredient (C. botulinim) as Botox, made by Allergan, which has been in the news lately, too.

In the iTWire article FDA to strengthen warnings on Botox type drugs, the FDA is requiring stronger warning labels on all drugs made with C. botulinim because of the possibilities of breathing and swallowing problems, along with rare reported cases of hospitalization and death.

When C. botulinim is injected into a wrinkle the toxin interferes with (the release of acetylcholine within the neuromuscular junction of) nerve impulses within the muscles, and, thus, causes paralysis of those local muscles.

The muscles are then unable to contract for several months.

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