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Medical first: Stem cells used for windpipe transplant

Science - Biology



The University of Bristol news release reported the comments of Dr. Martin Birchall, a Bristol professor, who said the transplant showed “the very real potential for adult stem cells and tissue engineering to radically improve their ability to treat patients with serious diseases."

It adds, "We believe this success has proved that we are on the verge of a new age in surgical care.” [University of Bristol: “Adult stem cell breakthrough”]

Ms. Castillo, the patient, stated after the successful operation: “Above all I would like to thank Dr. Macchiarini and his medical team who did the research, for the time and dedication they devoted to my case to make sure that everything turned out alright.”

Clinical trials will be performed, based on Ms. Castillo's surgery and recovery, after she has had her transplanted trachea for over six months.

The authors of the study include: Paolo Macchiarini, Philipp Jungebluth, and Tetsuhiko Go (all from the Department of General Thoracic Surgery, Hospital Clinic, Barcelona, Spain); M Adelaide Asnaghi and Sara Mantero (Bioengineering, Politecnico di Milano, Milan, Italy); Louisa E Rees, Amanda Dodson, and Martin A Birchall (Clinical Sciences at South Bristol, Faculty of Clinical Medicine and Dentistry, University of Bristol, Bristol, U.K.).

And, Tristan A Cogan, Sally C Dickinson, and Anthony P Hollander (Department of Cellular and Molecular Medicine, University of Bristol, Bristol, U.K.); Jaume Martorell (Immunology, Hospital Clinic, Barcelona, Spain) and Silvia Bellini, Pier Paolo Parnigotto, and Maria Teresa Conconi (Pharmaceutical Sciences, University of Padua, Padua, Italy).

For additional information on such transplants, go to the American Association for Thoracic Surgery.

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