The good news is that the protocol isn't new. It's been talked about and written about for most of this decade. You can be certain the big players - Cisco, major ISPs, the like - all have this matter under control in equipment manufactured and installed or upgraded in recent years.
Further, DNSSEC has been rolling out progressively across the mass collection of root name servers for several months now with few, if any, ill effects.
Still, if you have any concerns be sure to test your company, your home, your network using tools like OARC's DNS reply size test server.
Let's knock this problem over before the rest of the world get startled this time.