The disappointing results came as Microsoft earlier this week moved to slash prices of the iPad competitor worldwide, including in Australia.
Broader results showed that Microsoft's revenue for the quarter was $19.9 billion, compared to the average $20.7 billion that Yahoo! Finance analysts had predicted.
And Microsoft brought in a disappointing $77.8 billion for the 2013 fiscal year, down from the $78.7 billion expected by analysts.
Microsoft's profit figures were another disappointment for investors, with analysts expecting quarterly earnings of $0.75 per share, which instead turned out to be $0.59 per share.
The company's shares tumbled 6.3% in after-hours trading to $33.22, off $2.22.
The results showed Microsoft, while still extremely profitable, is struggling to shake off concerns that it hasn't fully worked out what it wants from Windows 8 yet.
Microsoft's new CFO Amy Hood said the overall downturn in the PC market was largely to blame for the poor results, but said the future was still promising for the company.
"While we have work ahead of us, we are making the focused investments needed to deliver on long-term growth opportunities like cloud services," she said.
Rick Sherlund, an analyst with Nomura Securities, told the Wall Street Journal the news was surprisingly bad across the company, with nearly all of the business units missing the company's prior expectations.
"It was a whiff across the board," he said. "It's the fourth quarter in a row that they've missed their guidance for the major segments of their business."
Microsoft CEO Steve Ballmer announced a massive restructure of the company last week.