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Science Science shows why first cigarette produces nausea or pleasure
Science Science shows why first cigarette produces nausea or pleasure | Science shows why first cigarette produces nausea or pleasure |
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| by William Atkins | |
| Sunday, 10 August 2008 | |
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Page 3 of 3 According to the Addiction news article, “The new findings linking first smoking experiences, smoking habits, and genetic variation build on previous research by Ovide Pomerleau and Cynthia Pomerleau, Ph.D., at U-M. In studies conducted over a 10-year span, they documented a link between nicotine-dependent smoking and positive first smoking experiences.” According to the WebMD article, Pomerleau says, "It really is a triple whammy, People with this genetic makeup find smoking pleasurable from that first cigarette and they are more likely to get addicted and develop lung cancer." The discovery of this study, along with previous related studies, show that new, more effective therapies are possible at treating people addicted to nicotine. Pomerleau states, "Things are moving really fast in this field. We are making new discoveries all the time." [WebMD] He adds that more effective treatments are possible within a few years. The scientific paper summarizing the research study is entitled “Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking.” It was published in the journal Addiction (2008; 103: 1544-1552). Its authors are: Richard Sherva, John P. Rice, Laura J. Bierut and Rosalind J. Neuman of the Department of Psychiatry at the Washington University School of Medicine; Kirk Wilhelmsen of the Department of Genetics and Neurology at the Carolina Center for Genome Sciences; Ovide Pomerleau, Cynthia S. Pomerleau and Sandy M. Snedecor of the University of Michigan Department of Psychiatry; and Scott A. Chasse of the Department of Biochemistry and Biophysics at the University of North Carolina.
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