The conference is scheduled to be held at the Australian National University in Canberra from January 28 to February 2 next year.
Sir Tim, who invented the web in the late 1980s, is now the director of the World Wide Web (W3) Consortium which looks after development of the medium around the world.
He is attending the Linux conference as part of a visit to Australia which is supported by a number of sponsors. He will also visit Melbourne and Sydney during his stay in the country.
He is the best-known tech celebrity to keynote at any of the Linux conferences; next in line would be one of the inventors of TCP-IP, Vint Cerf, who was a keynote speaker in 2011.
The only person with a higher profile to attend the conference has been Linux creator Linus Torvalds but he has never been a keynote speaker.